TOXIC DYNAMICS

Toxic dynamics, termed pharmacodynamics in pharmacology, describes the dynamic interactions of a toxicant with a biological target and its biological effects A biological  target, also known as the site of action, can be necessary proteins, ion channels, DNA, or a variety of other receptors. When a toxicant go in for an organism, it can linkup with these receptors and produce structural or functional alterations. The appliance of action of the toxicant, asset on by a toxicant’s chemical properties, will determine what receptors are targeted and the overall toxic effect at the cellular level and organismal level. Toxicants have been bought together as stated to their chemical properties by way of quantitative structure- activity relationships (QSARs), which allows prediction of toxic action based on these properties. Endocrine interrupt chemicals (EDCs) and carcinogens are examples of classes of toxicants that can act as QSARs. EDCs mimic or stop correspondence activation normally caused by natural steroid hormones.

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