Abdul Rohim Tualeka, Fransisca Anggiyostiana Sirait and Fatma Nuriyanti Mochtar
Airlangga University, Indonesia
Title: Correlation between benzene concentrations with trans and trans-muconic acid
Biography
Biography: Abdul Rohim Tualeka, Fransisca Anggiyostiana Sirait and Fatma Nuriyanti Mochtar
Abstract
Shoe maker workers risk exposure to benzene derived from the glue used. Benzene belongs to the category of carcinogen A1 (confirmed human carcinogen), meaning that benzene has been confirmed and proven to be a carcinogen in humans. In chronic exposure to benzene shows an effect on cellular and humoral immunity. Benzene evaporates into the air so quickly that it is possible to be inhaled by the workers. The objectives of this study were to measure benzene vapor levels in the working environment, to study worker characteristics, to measure trans levels, to transmuconic acid workers, and to analyze the exposure relationship of benzene vapor and the characteristics of workers with trans levels, trans-muconic acid workers. The method used to measure benzene vapor levels in the working environment is the GC/FID (Flame Ionization Detector) chromatography method, measuring trans, trans-muconic acid levels using Liquid Chromatography Mass Spectra (LC-MS). This study includes 20 research subjects and out of which 8 respondents experienced increased levels of trans, trans-muconic acid and benzene vapor levels in the working environment of 0.0129-2.3330 ppm. The result of the calculation of worker risk characteristics was obtained RQ>1=65% (13 respondents had non-cancer exposure effect) and ECR>10-4=75% (15 workers at risk of cancer) due to benzene exposure.